Keep your head up. Never walk around looking down. Said to me by a custodian at my previous job. Wonderful man.

If you regret this, then you should not date. Really.

You have to enjoy dating for the ride, both figuratively and literally in this case.

99% of all the first dates you go on will end in eventual "failure." It's part of the deal.

It's not about there being anything wrong with you or evil about them or whatever... it's just the way it is.

And, you're right-- you aren't going to see her again, and that's also just part of dating.

True, I don't see things going very well at all.

Another, smaller 9V battery?

I would say “hold on , when did I get a girlfriend?”

What kind of absolute loser cheers these chuds being released.

Tate needs hair plugs. And a chin implant. He looks like the most beta bitch I've ever seen.

There is gonna be a major pump after the RS as the number of shares will make pumping viable again.

After that it'll drop like a stone in the dump phase again.

The more I read about this guy, the more I realize how his actions could fuck other growers if the feds start snooping their social media thanks to him.

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It is ready. It's them being cheap assholes and not spinning enough servers up.

If you can afford it, never, as long as you expect them to pay you back (in a reasonable way) after they live on their own.

Great question OP! I have a PhD in this topic.

TLDR:

• Drugs such as chemotherapeutic agents that damage the nervous system can enhance pain
• The term to describe this enhancement is hyperalgesia
• The processes that cause it are peripheral sensitisation and central sensitisation
• LTP, or an increase in ion-channel expression at the neuronal synapse, is one of the many mechanisms involved
• In the case of LTP, the main neurotransmitter is glutamate

Analgesics are drugs that work by reducing pain, and the opposite of this would be drugs that increase pain. The term used to describe an increased pain response is hyperalgesia.

An example of a condition that can lead to increased pain is chemotherapy-induced peripheral neuropathy (CIPN), which is caused by chemotherapeutic agents that damage the nervous system. This damage can result in peripheral sensitisation, through hyperalgesia and ectopic firing. Peripheral sensitisation occurs when the threshold for activation of high-threshold pain receptors is lowered, and their responsiveness is enhanced (hyperexcitability) when they are exposed to inflammatory mediators and damaged tissues. This can lead to central sensitisation as well, but that's a more complicated process [1].

Long-term potentiation (LTP) is one mechanism that can lead to sensitisation through increasing ion channel expression at the synapse. It occurs when the connection between neurons is strengthened due to increased firing frequency between them. Some studies have shown that ketamine, which is an NMDA antagonist that inhibits LTP, can have analgesic effects in cases of peripheral sensitisation [2]. This shows that LTP is one of the mechanisms involved in sensitisation.

P.S.

There are also surgical methods to enhance the pain response which we do in research to model disease. One example is chronic constriction of the infraorbital nerve (CCI-ION) to model trigeminal neuralgia.

Then there is a name for what yoir looking for. Decriminalization.

Why are you so highly regarded?

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The battle of Cannae. I want to see the battle and i want to listen to the discussions between Hannibal and his genrals before and especially after the battle

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Former cashier here, but we’re human too, not robots. It shouldn’t be a surprise at how often customers tend to think this way.

Usually it's whenever the parent dies. Even then though, there's sometimes inheritance

It depends on the game and the person. Starcraft is absolutely more strenuous than golf. If I play starcraft at 200+ apm for two hours I have to lay down to let my back and wrist recover. I can easily golf for two hours just fine.

Completely depends on the game, if you're a mouse and keyboard player, try playing Apex Legends with a controller and see how much better you suddenly get.

So that you would have a question to ask in reddit, which would make you like part of a group.

Ahhh that makes sense, I just used my HRs calculator and looks like my paychecks increased by $100

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I wish Reddit would let me copy/paste a previous comment text but I can't. I listed things in a previous comment above ours.