Is there a genetic disease where the heterozygote has more severe disease symptoms than the homozygote? Submitted by Altranite- t3_11damcv on February 27, 2023 at 12:25 PM in askscience 53 comments 973
DurianBig3503 t1_ja8q9ko wrote on February 27, 2023 at 5:58 PM Theoretically, if; Both alleles are transcriptionally active. It forms a homopolymer. Both forms are functional. Then it could happen that either homozygote functions better than the heterozygote. I have never seen it. Permalink 5
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